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Holly Jones-Taggart
PhD

Associate Professor

Faculty of Health Sciences

Contact information

Science Building - Room 2016
North Oshawa
2000 Simcoe Street North
Oshawa, ON L1H 7K4

905.721.8668 ext. 2539

holly.jonestaggart@uoit.ca


Research topics

  • cellular response to external stimuli
  • molecular manipulation techniques
  • technology-enhanced strategies for delivery of health sciences education

Background

After earning her PhD degree in Molecular Biology from Western University in London, Ontario, Dr. Holly Jones-Taggart spent three years in a post-doctoral research position at the Ontario Cancer Institute at Princess Margaret Hospital in Toronto, Ontario.

Education

  • PhD in Molecular Biology University of Western Ontario in London, Ontario
  • BScH in Biology Queen's University in Kingston, Ontario

Courses taught

Courses taught (past and present) at the undergraduate level:

  • Human Genetics in Society
  • Science Bridge
  • Altered Physiology: Mechanisms of Disease I & II
  • Anatomy and Physiology I & II
  • Cell Biology
  • Genetics & Molecular Biology

Courses taught (past and present) at the graduate level:

  • Research in Applied Biosciences
  • Special Topics in Health Sciences Research

Research and expertise

  • Applying molecular manipulation techniques to understand biological pathways in healthy and diseased cells.
  • Focusing on micro-environmental cues that trigger signaling pathways involved in proliferation, survival, migration, inflammatory response and metastatic behaviour of human cells.
  • Investigating technology-enhanced strategies for delivery of health science education that integrates content within the course and between related courses, and how to emphasize its clinical application within the Health Sciences programs.

At UOIT, Dr. Jones-Taggart’s laboratory-based research involves investigating cancer cell responses to extracellular stimuli that are known activators of motility, growth and survival pathways in cells—how environmental toxins and hormones affect gene expression and cell signalling. She is also involved in projects concerning nutritional genomics education and case-study integration into health sciences courses because of her interest in technology-enhanced teaching and learning.

  • Master of Applied Bioscience (MSc) supervisor for Farrah Edun (2015 to 2017).
  • Master of Applied Bioscience (MSc) supervisor for Kyle Dobby (2013 to 2015): Examining Effects of Milk Ferment Components on Endothelial Cell Signaling in Pro-Inflammatory Pathways.
  • Master of Applied Bioscience (MSc) supervisor for Sara Mannan (2009 to 2011): The Effects of Endosulfan on Human MCF-7 Breast Cancer Cells.
  • Master of Applied Bioscience (MSc) supervisor for Lisa J. Praetorius (2007 to 2009: The Regulation of RANK and RANKL mRNA Expression Through Activation of the JAK/Stat5a Pathway in Human Breast Cancer Cell Lines.
  • NSERC and Dairy Farmers of Canada. PI: J. Green-Johnson CoPI: H Jones Taggart and J Strap. Investigating the Anti-Atherogenic Potential of Fermented Dairy Products.
    • 2013, $160,600
  • J.P. Bickell Foundation—Medical Research Grant. Jones-Taggart, H and Sanchez, O. Environmental Toxins and Breast Cancer.
    • 2008 to 2011, $68,500
  • University of Ontario Institute of Technology (UOIT) Teaching Innovation Fund—Education Research. Vogel, E, Jones-Taggart, H, Ryan-Harshman, M and Green-Johnson, J. You Are What You Eat.
    • 2008 to 2009, $6,500
  • Canadian Institutes of Health Research (CIHR)/SYNAPSE Strategic Training Initiative in Health Research (STIHR) Youth Mentorship Program. Green-Johnson, JM, Smith, W, Forrester, S, Jones-Taggart, H, Vogel, E and Sanchez, O. UOIT’s Science Research for Health Day.
    • 2006 to 2008, $15,000
  • UOIT Teaching Innovation Fund—Education Research. Green-Johnson, J, Vogel, E, Ryan-Harshman, M and Jones-Taggart, H. Virtual Shopping for Functional Foods: An Animated Approach to Nutrition Education.
    • 2007 to 2008, $5,000
  • Canadian Foundation for Dietetic Research—Nutrigenomics Research.Vogel, E, Ryan-Harshman, M, Jones-Taggart, H, Green-Johnson, J, Anderson, K, Austin, Z and Castle, D. The Interface Between Nutrition And Genes: Nutritional Genomics And Dietetic Professional Practice.
    • 2005 to 2006, $30,000
  • UOIT Teaching Innovation Fund—Education Research. Jones-Taggart, Hand Sanchez, O.  Development and Use of Online Health Sciences Case Studies.
    • 2004 to 2005, $5,000

Involvement

  • Selected publications
    • Jones Taggart, H and Sanchez, O. (2016). Integrating Basic Sciences in the Medical Laboratory Sciences Curriculum: A Case Study of Strategies and Approaches. AMEE MedEdPublish.
    • Harshman, M, Vogel, E, Jones-Taggart, H, Green- Johnson, J, Castle, D, Austin, Z and Anderson, K (2008). Nutritional Genomics and Dietetic Professional Practice: A Review. Canadian Journal of Dietetic Practice and Research, 69(4), 177-82.
    • Jones, DH, Nakashima, T, Sanchez, OH, Kozieradzki, I, Komarova, SV, Sarosi, I, Morony, S, Rubin, E, Sarao, R, Hojilla, CV, Komnenovic, V, Kong, YY, Schreiber, M, Dixon, SJ, Sims, SM, Wada, T, Khokha, R and Penninger, JM (2006). Regulation of Cancer Cell Migration and Bone Metastasis by RANKL. Nature, 440, 692-696.
    • Jones, DH, Li, TY, Arystarkova, E, Barr, KJ, Wetzel, R, Peng, J, Markham, K, Sweadner, K, Fong, G-H and Kidder, GM (2005). Na+, K+-ATPase from Mice Lacking the Subunit (FXYD2) Exhibits Altered Na+ Affinity and Decreased Thermal Stability. Journal of Biological Chemistry, 280(19), 19003-11.
    • Jones, DH, Kong, YY and Penninger, JM (2002). Role of RANKL and RANK in Bone Loss and Arthritis. Annals of the Rheumatic Diseases, 61 (Suppl 2), ii32-9.
  • Presentations
    • Ryan-Harshman, M, Vogel, E, Atkins, B, McLean, J, Myco, C and Jones Taggart, H. Public- Private Partnership: Successful Development of a Social Marketing Course. INTED2016: 10th International Technology, Education and Development Conference. March 7 to 9, 2016, Valencia, Spain.
    • Jones Taggart, H, Strap, J and Green- Johnson, J. Investigating Anti- Atherogenic Potential of Fermented Dairy Products. Invited speaker: Faculty of Health Science Seminar Series, March 2016, UOIT, Oshawa, Ontario.
    • Jones Taggart, H. RANK and RANKL in human physiology and disease. Invited speaker: Applied Biosciences Research Seminar Series, February 2011, UOIT, Oshawa, Ontario.
    • Sanchez, O and Jones Taggart, H (June 2007). Advancing the Educational Use of Case Studies Across a BScN Program in a Mobile Learning Environment. Rutgers College of Nursing 25th Annual International Computer and Technology Conference, San Francisco, California.
    • Vogel, E, Ryan-Harshman, M, Green-Johnson, J, Jones Taggart, H, Castle, D, Austin, A and Anderson K (February 13 to 14, 2007). Nutritional Genomics and Professional Practice: More Questions than Answers. Nutrition File Seminar: In Pursuit of the Perfect Diet sponsored by Alberta Milk, University of Alberta, Dietitians of Canada and Canadian Dairy Products, Edmonton and Calgary, Alberta.
    • Taggart, H, Sanchez, O and Hostetler, R (May 2006). Online Case Studies: Our Current Research and New Directions. Rutgers College of Nursing 24th Annual International Computer and Technology Conference, Toronto, Ontario.
    • Sanchez, O and Jones Taggart, H (April 2005). Case Studies in Health Sciences Education: Enhancing Student Interactivity With Technology. Rutgers College of Nursing 23rd Annual International Computer and Technology Conference, Atlanta, Georgia.

    Poster presentations

    • Strelchuck, C and Jones Taggart, H. Alterations in gene and protein expression after exposure of MDA-MB-231 cells to isobutylparaben. American Association for Cancer Research. April 1 to 5, 2017, Washington, D.C.
    • Jeffrey, M., Jones Taggart, H., Strap J.L and Green-Johnson J.M. Evaluation of immunomodulatory effects of Lactobacillus rhamnosus R0011 fermented milk on production of pro-atherogenic cytokines: A comparison between THP-1 and U937 human monocyte cells. Annual Meeting of the American Association of Immunologists, May 8 to 12, 2015, New Orleans, Louisiana.
    • Adams, C., Green-Johnson, J.M., Jones Taggart, H., and Strap, J.L. In vitro antihypertensive and immunomodulatory properties of casein-derived peptides liberated by two strains of lactic acid bacteria. Canadian Society of Microbiologists, June 15 to 18, 2015, Regina, Saskatchewan.
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